Cytogenetic Examination Due to Suspected Radiation Damage – A Case Report

Abstract

Tumors can develop years after the irradiation due DNA damage caused by ionizing radiation. In cases when affected people didn’t wear any personal dosimeter, the received dose can be estimated with different biodosimetry tools. These methods can be used to determine the individual radiosensitivity of the soldiers deploying to mission and with the examinations of returnees with complaints in case of radiation injury the proper therapy can be selected as well. This paper describes an examination of two people with complaints, as radiation damage was suspected.

The studies were performed by the HDF Medical Center Scientific Research and Laboratory Institute by micronucleus test and dicentric chromosome analysis. The results obtained with the micronucleus test showed elevated values compared to the reference value of our laboratory, but the later performed more specific dicentric chromosome analysis did not confirm the radiation damage.